87Occult gastrointestinal stromal tumor – Sohu health|Occult gastrointestinal stromal tumor – Sohu health3

The presence of occult gastrointestinal stromal tumors – the Sohu is a common cancer of the stomach, and for gastrointestinal stromal tumors, I believe many people have not heard. The tumor was previously considered a rare disease, with about 15 new cases per million people. But at present, its incidence has increased gradually, is not uncommon, the disease harm should not be overlooked, causing serious threat to life when. It is a kind of tumor with different malignant potential, which is similar to many digestive diseases. Although more than half of the small stromal tumor is benign tumor characteristics, but with the increase of gastrointestinal stromal tumor, malignant transformation and metastasis part, the first diagnosis of gastrointestinal stromal tumor patients, more than 50% of the patients had liver metastasis and peritoneal metastasis, of which 65% patients will transfer to the liver therefore, deadly. Although more and more patients are suffering from the threat of gastrointestinal stromal tumors, but the disease is still not enough attention to the public, leading to this phenomenon is the main cause of the disease early occult. Causes: first, the environmental factors of gastric stromal tumors is an important factor in the production of A. Gastric stromal tumor and cause the local eating habits are closely related, often eat moldy, salted, smoked food, or excessive intake of salt can increase the risk of gastric stromal tumors occur between. Smoked fish contain more 3 4-, benzopyrene, moldy food contains a lot of mycotoxins, nitrite class pickled foods, these substances have carcinogenic effects. So we should develop good habits, refuse junk food, eat more fruits and vegetables. Two research on genetic factors that cause genetic gastric stromal tumors has the relationship between the family members of the patients with gastric stromal tumor incidence is higher than the ordinary people, these people are due to the living environment and eating habits similar to increase gastric stromal tumor incidence, it also shows that genetic factors play the more important role in the pathogenesis of gastric stromal tumors. Frequent occurrence of c-kit mutations in gastrointestinal stromal tumors. The tumor can also occur in the abdominal soft tissue such as omentum, mesentery or peritoneum, and have the same morphological, immunophenotypic and molecular genetic characteristics as gastrointestinal stromal tumors. In the aspect of molecular genetics, the mutation of c-kit gene in gastrointestinal stromal tumors () is common. Gastrointestinal stromal tumors are very difficult to diagnose. It grows in the abdominal cavity, and the abdominal cavity space is very large, so in the early tumor volume is often no obvious symptoms, a lot of patients with tumors in the routine examination of the accidental discovery. With the increase of tumor patients, clinical symptoms often include abdominal distension and pain, melena and anemia, but these symptoms are usually nonspecific, easy to confuse and colorectal cancer, gastric cancer, gastric ulcer, which leads to the patient is often not timely symptomatic treatment. Although it is a kind of malignant tumor, it is an effective treatment for resectable malignant tumor. However, the recurrence rate of gastrointestinal stromal tumor is still as high as 40% ~ 80%. Fortunately, because of its source and news